Rheumatology

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Summary

Our role
Our specialities
Research
Publications
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Our role

The Paediatric Rheumatology Unit treats diseases of the bones, joints and muscles of the child. Paediatric rheumatology covers various rheumatoid inflammatory diseases, rare diseases that can be the cause of chronic pain lasting several years. These diseases can be associated with symptoms affecting the skin, eyes, kidneys, lungs, etc. 

Our unit maintains a rich cooperation with a number of specialists concerned by these diseases as well as with paramedical staff. This multidisciplinary approach is a cornerstone for the patient's care pathway: for diagnosis and therapeutic follow up as well as pain management and the transition to an adult unit.

Our specialities

The Paediatric Rheumatology Unit treats the following inflammatory systemic diseases: 

  • Juvenile idiopathic arthritis
  • Connective tissue diseases: systemic lupus erythematosus, dermatomyositis, systemic scleroderma
  • Vasculitis: Kawasaki disease, Henoch-Schönlein purpura, polyarteritis nodosa,   Behçet disease
  • Recurrent fever  and other auto-inflammatory syndromes 
  • Familial Mediterranean fever,  cryopyrinopathies, TRAPS, MKD, and other rarer syndromes
  • PFAPA
  • Multifocal non-infectious osteomyelitis
  • Inflammatory granuomatous disease
  • Uveitis

The department's activity is concentrated in a number of areas: 

  • outpatient consultation
  • the day hospital for children receiving treatment by repeated perfusions 
  • the monitoring of hospitalised children to establish diagnoses and decide treatment 
  • transition from adolescence to an adult team, assured progressively during joint consultations with our rheumatologist who is present on the same campus.
Recherche rhumato

Research

The unit participates actively in a number of multicentre research projects, such as: 

  • clinical trials enabling patients to access new treatments
  • academic studies to deepen knowledge of rheumatic diseases and optimise their long-term treatment.

The unit cooperates with associations of national experts such as the  Belgian Working Group of Pediatric Rheumatology, the Belgium Network for Auto-Inflammatory Diseases and at European level with PreS, PRINTO and SOFREMIP.

Our team

huderf informations pratiques

Our specialists

Publications

Serum calprotectin (S100A8/A9): A promising biomarker in diagnosis and follow-up in different subgroups of juvenile idiopathic arthritis (2021)

  • Authors : La, C., Lê, P.Q., Ferster, A., Goffin, L., Spruyt, D., Lauwerys, B., Durez, P., Boulanger, C., Sokolova, T., Rasschaert, J., Badot, V.
  • Journal : RMD Open, 7 (2), art. no. 001646

Tapering Canakinumab Monotherapy in Patients With Systemic Juvenile Idiopathic Arthritis in Clinical Remission: Results From a Phase IIIb/IV Open-Label, Randomized Study(2021)

  • Authors : Quartier, P.,… et al,… Goffin, L., Le, P.-Q., … et al and Akoghlanian, S., the Paediatric Rheumatology International Trials Organisation and the Pediatric Rheumatology Collaborative Study Group.
  • Journal : Arthritis and Rheumatology, 73 (2), pp. 336-346.

Rapid and Sustained Long-Term Efficacy and Safety of Canakinumab in Patients With Cryopyrin-Associated Periodic Syndrome Ages Five Years and Younger (2019)

  • Authors : Brogan, P.A., Hofer, M., Kuemmerle-Deschner, J.B., Koné-Paut, I., Roesler, J., Kallinich, T., Horneff, G., Calvo Penadés, I., Sevilla-Perez, B., Goffin, L., Lauwerys, B.R., Lachmann, H.J., Uziel, Y., Wei, X., Laxer, R.M.
  • Journal : Arthritis and Rheumatology, 71 (11), pp. 1955-1963.